Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Born-Haber Cycle02:44

The Born-Haber Cycle

25.4K
Lattice Energy 
25.4K
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

1.9K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
1.9K
Computed Tomography01:10

Computed Tomography

8.7K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
8.7K
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

306
Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
306
Special Features of Adaptive Immunity01:20

Special Features of Adaptive Immunity

3.3K
The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
3.3K
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

665
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
665

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cuticular drusen: a case report with 20-year follow up.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026
Same author

Acute Paracentral Scotoma Following Cosmetic Penile Filler Injection.

Retinal cases & brief reports·2026
Same author

Evidence and Consensus Based Guidelines for Imaging in Tubercular Choroiditis. Multimodal imaging in Uveitis (MUV) Taskforce: Report 17.

Ophthalmology. Retina·2026
Same author

Severe Chloroquine Retinal Toxicity.

Ophthalmology. Retina·2026
Same author

Evidence and Consensus-Based Guidelines in Vogt-Koyanagi-Harada Disease. Multimodal Imaging in Uveitis (MUV) Taskforce Report 16.

Ophthalmology. Retina·2026
Same author

Deconstructing White Dot Syndromes-Multimodal Imaging in Uveitis (MUV) Taskforce: Report 11.

American journal of ophthalmology·2026

Related Experiment Video

Updated: Feb 5, 2026

Born Normalization for Fluorescence Optical Projection Tomography for Whole Heart Imaging
16:44

Born Normalization for Fluorescence Optical Projection Tomography for Whole Heart Imaging

Published on: June 2, 2009

10.8K

VISUAL FUNCTION AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FEATURES IN CHILDREN BORN PRETERM.

Siva Balasubramanian1,2, Enrico Borrelli1,2,3, Marcela Lonngi2,4

  • 1Doheny Image Reading Center, Doheny Eye Institute, Los Angeles, California.

Retina (Philadelphia, Pa.)
|September 5, 2018
PubMed
Summary

Preterm children show altered foveal structure and vasculature, impacting visual acuity. These optical coherence tomography angiography findings highlight vision risks in preterm infants.

More Related Videos

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
07:08

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Published on: January 10, 2019

10.6K
Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

5.3K

Related Experiment Videos

Last Updated: Feb 5, 2026

Born Normalization for Fluorescence Optical Projection Tomography for Whole Heart Imaging
16:44

Born Normalization for Fluorescence Optical Projection Tomography for Whole Heart Imaging

Published on: June 2, 2009

10.8K
Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
07:08

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Published on: January 10, 2019

10.6K
Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

5.3K

Area of Science:

  • Ophthalmology
  • Developmental Biology
  • Medical Imaging

Background:

  • Preterm infants face higher risks of visual impairments, including retinopathy and refractive errors.
  • Foveal development is crucial for sharp central vision, and its disruption can lead to lasting visual deficits.

Purpose of the Study:

  • To explore the connection between foveal parameters measured by optical coherence tomography angiography (OCTA) and visual function in preterm children.
  • To identify specific OCTA-derived foveal metrics associated with visual impairment in this population.

Main Methods:

  • Eighty eyes (32 preterm, 48 controls) underwent comprehensive eye exams and OCTA imaging.
  • Key foveal morphologic (depth, thickness, retinal area) and vascular (avascular zone, vessel density) parameters were quantified.
  • Best-corrected visual acuity (BCVA) was assessed and correlated with OCTA findings.

Main Results:

  • Preterm children exhibited significantly worse BCVA compared to controls.
  • Significant differences in foveal morphology (increased thickness/area, decreased depth) and vasculature (decreased avascular zone, increased vessel density) were observed in preterm eyes.
  • Worse visual acuity correlated with shallower foveal depth, smaller foveal avascular zone, increased central foveal thickness, and larger inner retinal area.

Conclusions:

  • Foveal morphological and vascular alterations in preterm children are linked to impaired visual function.
  • OCTA reveals distinct changes in the fovea of preterm individuals, offering potential biomarkers for visual deficits.
  • Longitudinal studies are recommended to track these changes and their long-term impact on vision.