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Tilted-CAIPI for highly accelerated distortion-free EPI with point spread function (PSF) encoding.

Zijing Dong1, Fuyixue Wang2,3, Timothy G Reese2

  • 1Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, China.

Magnetic Resonance in Medicine
|September 20, 2018
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Summary
This summary is machine-generated.

This study introduces tilted-CAIPI, a novel technique for fast, distortion- and blurring-free imaging. It significantly accelerates imaging acquisition while maintaining high image quality and signal-to-noise ratio.

Keywords:
diffusion imagingdistortion correctionecho-planar imagingparallel imagingpoint spread function mapping

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Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Image Reconstruction
  • Medical Imaging

Background:

  • Echo-Planar Imaging (EPI) with point-spread-function (PSF) mapping offers distortion- and blurring-free imaging but requires long acquisition times.
  • Accelerated imaging techniques are crucial for improving MRI efficiency and patient comfort.

Purpose of the Study:

  • To develop a novel acquisition/reconstruction technique, "tilted-CAIPI," for highly accelerated, distortion- and blurring-free EPI imaging.
  • To achieve >20x acceleration for PSF-EPI while preserving image quality.

Main Methods:

  • Proposed "tilted-CAIPI" method optimizes k-space trajectory with B0-inhomogeneity-informed reconstruction.
  • Exploited signal correlation in PSF-EPI and coil sensitivity for acceleration.
  • Integrated susceptibility-induced phase accumulation as an additional encoding.
  • Developed self-navigated phase correction for diffusion imaging.

Main Results:

  • Demonstrated highly accelerated imaging without distortion or blurring in vivo brain experiments.
  • Achieved high-quality, high-SNR imaging at 0.8-1 mm resolution using only 8 shots per simultaneous slice group.
  • Tilted-CAIPI successfully implemented with partial Fourier and simultaneous multislice for further acceleration.

Conclusions:

  • Tilted-CAIPI enables fast, distortion- and blurring-free imaging with high SNR.
  • Whole-brain T2-weighted, T2*-weighted, and diffusion imaging acquired in 15-60 seconds.
  • The method significantly advances accelerated MRI acquisition techniques.