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Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
Published on: August 16, 2021
Continuous-Flow Left Ventricular Assist Device-Related Gastrointestinal Bleeding
Ju H Kim1, Donald F Brophy2, Keyur B Shah3
1Advanced Heart Failure and Transplant, Methodist DeBakey Cardiology Associates, Houston Methodist Hospital, 6550 Fannin Street, Smith Tower, Suite 1901, Houston, TX 77030, USA.
Abstract:
Continuous-flow (CF) left ventricular assist devices (LVADs) are a safe and durable therapeutic option for patients with advanced heart failure as a bridge to transplant or as destination therapy. Despite the remarkable technological advances in device design and increasing familiarity with the physiologic effects of CF, major complications such as gastrointestinal bleeding (GIB) continue to cause significant morbidity. The causes underlying CF-LVAD-related GIB are multifactorial. Accordingly, management strategies for CF-LVAD-related GIB encompass a wide range of therapeutic modalities. This article reviews the epidemiology, pathophysiology, risk factors, and treatment options for the management of this complex complication.
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