Prevalence of Diastolic Dysfunction in Type 2 Diabetes Mellitus

Area of Science:

• Cardiology
• Endocrinology
• Diabetology

Background:

• Diastolic dysfunction impairs ventricular filling, increasing heart failure risk.
• Diabetes mellitus is a significant risk factor for heart failure, independent of other conditions.
• Understanding diastolic dysfunction in type 2 diabetes is crucial for cardiovascular risk management.

Purpose of the Study:

• To determine the prevalence of diastolic dysfunction in type 2 diabetes mellitus patients.
• To investigate associations between diastolic dysfunction and patient demographics and risk factors.
• To identify key predictors for diastolic dysfunction in this population.

Main Methods:

• A study involving 90 patients with type 2 diabetes mellitus (age 30-60).
• Diastolic function was assessed using Doppler echocardiography.
• Data collected included age, gender, diabetes duration, HbA1c, lipids, and lifestyle factors.

Main Results:

• The overall prevalence of diastolic dysfunction was 47.8%.
• Prevalence significantly increased with age (30-39 yrs: 23.1% vs. 50-60 yrs: 65.8%) and diabetes duration (<5 yrs: 32.8% vs. >10 yrs: 75%).
• No significant association was found with HbA1c, dyslipidemia, BMI, smoking, or alcohol consumption.

Conclusions:

• Diastolic dysfunction is highly prevalent (47.8%) in type 2 diabetes mellitus.
• Increasing age and longer diabetes duration are associated with a higher prevalence of diastolic dysfunction.
• These findings underscore the importance of regular cardiac screening in aging diabetic patients with long-standing disease.