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Verrucous Carcinoma - Observations on 4 Cases
V Pătrașcu1, O Enache1, R Ciurea2
1Dermato-venerology Department, University of Medicine and Pharmacy of Craiova.
Current Health Sciences Journal
|December 21, 2018
Summary
Verrucous carcinoma (VC), a rare squamous cell carcinoma, presents in four distinct clinical forms. Early diagnosis through clinical and histopathological examination is crucial for effective management and monitoring.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Verrucous carcinoma (VC) is a rare, well-differentiated squamous cell carcinoma.
- It manifests in distinct clinical forms including oral florid papillomatosis, epithelioma cuniculatum, papillomatosis cutis, and Buschke-Löwenstein tumor.
- While etiopathogenesis is uncertain, Human Papillomavirus (HPV) involvement is widely accepted.
Observation:
- This study presents four patients, each exhibiting one of the four clinical forms of verrucous carcinoma.
- Diagnosis was established via comprehensive clinical examination and histopathological analysis.
- VC can affect both cutaneous and mucosal surfaces.
Findings:
- Verrucous carcinoma is characterized by slow, continuous evolution with invasion of underlying tissues.
- It has a high rate of recurrence but a very low risk of metastasis.
- Surgical excision with oncological safety margins is the primary therapeutic approach.
Implications:
- Accurate diagnosis requires correlating clinical presentation with histopathological findings and tumor behavior.
- Regular follow-up is essential due to the high risk of recurrence.
- Understanding the diverse clinical presentations of VC is vital for timely and appropriate patient management.
Keywords:
Buschke-Löwenstein tumorVerrucous carcinomaepithelioma cuniculatumoral florid papillomatosispapilomatosis cutis carcinoidesMore Related Videos
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