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Updated: Jan 28, 2026

Direct Drug Delivery to Kidney via the Renal Artery
Published on: April 17, 2021
[Renal risks of NSAIDs in endurance sports]
Elise Chabbey1,2, Pierre-Yves Martin2
1Service de néphrologie, HUG, 1211 Genève 14.
Abstract:
Endurance athletes, either professional or amateur, are consuming non steroidal anti-inflammatory drugs (NSAIDs) during their training and races. The goal is to decrease pain or to prevent a potential pain. These athletes, especially, the amateurs, do not do not know the side effects and have no medical supervision. In association with other risks factors such as overhydratation, NSAIDs increase the risk of exercise associated hyponatremia (EAH). Its frequency increases as the number of long distance events is increasing but it is still unknown. Risk of acute kidney injury increases also with the use of NSAIDs. These risks have to be known by physicians and athletes.
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