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What is an Experiment?01:12

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An experiment is a planned activity carried out under controlled conditions. The purpose of an experiment is to investigate the relationship between two variables. When one variable causes change in another, we call the first variable the explanatory or independent variable. The affected variable is called the response or dependent variable. In a randomized experiment, the researcher manipulates values of the explanatory variable and measures the resulting changes in the response variable. The...
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In a beam of charged particles created by a heated cathode, the particles move at different speeds. However, many applications need a beam with uniform particle speeds. An arrangement known as a velocity selector uses electric and magnetic fields to pick particles with a particular speed from the beam.
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Randomized Experiments01:13

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The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
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Improving Student Outcomes with an Adaptable Molecular Cloning Course-Based Undergraduate Research Experience
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iCURE (iterative course-based undergraduate research experience): A case-study.

Angela K Stoeckman1, Yingqi Cai2, Kent D Chapman2

  • 1Bethel University, Saint Paul, Minnesota, 55112.

Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology
|July 2, 2019
PubMed
Summary
This summary is machine-generated.

This study created an iterative course-based undergraduate research experience (CURE) linking two universities. The collaborative research project successfully engaged students in plant science discovery, leading to publications and improved attitudes toward research.

Keywords:
CUREPlant biochemistrylipidsterpenesundergraduate research

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Area of Science:

  • Plant Biotechnology
  • Biotechnology Education
  • Undergraduate Research

Background:

  • Traditional apprentice-based research is limited by faculty time and institutional resources.
  • Course-based undergraduate research experiences (CUREs) increase student access but designing semester-long projects is challenging.
  • Existing models like Inclusive Research Education Communities have limited impact on upper-level courses.

Purpose of the Study:

  • To develop an iterative CURE between two universities with different research infrastructures.
  • To foster collaboration between diverse undergraduate learning communities.
  • To investigate gene function and engineer bioproducts using a plant transient expression system.

Main Methods:

  • Implemented a collaborative, iterative CURE module across two institutions over two years.
  • Utilized a tobacco (Nicotiana benthamiana) transient expression system for gene function testing.
  • Focused on engineering valuable bioproducts in plant vegetative tissues.

Main Results:

  • Generated novel scientific discoveries leading to peer-reviewed publications.
  • Achieved cost benefits through shared resources and collaborative efforts.
  • Provided students with practical training for future independent research.
  • Observed improved student attitudes and engagement with scientific research.

Conclusions:

  • Iterative CUREs can effectively bridge institutional gaps and promote collaborative research.
  • This model enhances student learning, research skills, and scientific discovery.
  • The tobacco transient expression system is a viable platform for undergraduate research and bioproduct engineering.