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Hyperpolarized Xenon for NMR and MRI Applications
Published on: September 6, 2012
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Low fields but high impact: Ex-situ NMR and MRI
Yi-Qiao Song1, Shin Utsuzawa1, Yiqiao Tang1
1Schlumberger-Doll Research, 1 Hampshire Street, Cambridge, MA 02139, USA.
Journal of Magnetic Resonance (San Diego, Calif. : 1997)
|July 20, 2019
Summary
Miniaturized magnetic resonance (MR) devices offer significant opportunities for low-field Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI). Widespread adoption of MR technology hinges on advancements in low-field applications.
Area of Science:
- Physics
- Materials Science
- Biomedical Engineering
Background:
- Richard Feynman's 1959 lecture "There's plenty of room at the bottom" inspired nanotechnology.
- Magnetic Resonance (MR) technology, including Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI), has historically required large, high-field apparatus.
- The miniaturization of scientific instrumentation presents new avenues for established techniques.
Purpose of the Study:
- To explore the potential of low-field MR technologies, particularly Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI).
- To highlight the opportunities presented by miniaturized, ex-situ apparatus for MR applications.
- To advocate for low-field MR as a pathway to widespread MR technology adoption.
Main Methods:
- Conceptual framework based on Feynman's "room at the bottom" principle.
- Focus on miniaturized apparatus for ex-situ Magnetic Resonance (MR) applications.
- Argumentative approach advocating for low-field NMR/MRI.
Main Results:
- Identified a "plethora of opportunities" in low-field NMR/MRI with miniaturized systems.
- Emphasized the potential of ex-situ MR devices.
- Established a strong case for the necessity of low-field approaches for broader MR utilization.
Conclusions:
- Low-field Magnetic Resonance (MR) systems, especially when miniaturized, represent a significant frontier with vast potential.
- Ex-situ, low-field NMR/MRI devices are crucial for democratizing MR technology.
- Widespread application of MR technology is realistically achievable only through low-field methodologies.
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