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An Innovative Strategy for the Effective Reduction of MDR Pathogens from the Nosocomial Environment

Elisabetta Caselli1,2, Maria D'Accolti3,4, Irene Soffritti3,4

  • 1Section of Microbiology and Medical Genetics, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. csb@unife.it.

Advances in Experimental Medicine and Biology
|July 20, 2019
PubMed

Insights

Antimicrobial resistance (AMR) poses a significant threat to public health. This study explores a novel probiotic bacteria sanitation strategy to stably reduce pathogen and AMR surface loads in hospitals, aiding infection control.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • Antimicrobial resistance (AMR) is a critical global health concern, threatening the efficacy of modern medical treatments.
  • Hospital-acquired infections and the spread of resistant pathogens are exacerbated by conventional sanitation limitations.
  • The hospital environment acts as a reservoir for pathogens, necessitating advanced control strategies.

Purpose of the Study:

  • To investigate an innovative sanitation strategy using probiotic bacteria.
  • To assess the efficacy of probiotics in reducing pathogen and antimicrobial resistance loads on surfaces.
  • To evaluate the potential of this approach for antimicrobial resistance and infection prevention and control.

Main Methods:

  • Studied an innovative sanitation strategy employing probiotic bacteria.
  • Monitored the reduction of pathogen surface load.
  • Assessed the impact on antimicrobial resistance (AMR) levels.

Main Results:

  • The probiotic sanitation strategy demonstrated a stable reduction in surface pathogen load.
  • The system effectively reduced antimicrobial resistance (AMR) associated with surface pathogens.
  • Data suggest a significant contribution to antimicrobial resistance control.

Conclusions:

  • Probiotic bacteria offer a promising approach for stable reduction of surface pathogens and their antimicrobial resistance (AMR).
  • This innovative sanitation method may serve as a valuable tool in hospital infection prevention and control strategies.
  • The findings support the integration of probiotic-based sanitation for broader antimicrobial resistance management.
Keywords:
Antimicrobial resistanceHealthcare-associated infectionsHospital environmentProbioticsSanitation strategy

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