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Updated: Jan 3, 2026

Development, Characterization, and Evaluation of CAGE-based Ionic Liquid Systems for Transdermal Delivery
Published on: September 26, 2025
Ionic Liquids for Therapeutic and Drug Delivery Applications
Simran K Zandu1, Hitesh Chopra1, Inderbir Singh1
1Chitkara College of Pharmacy, Chitkara University, Punjab, India.
Ionic liquids (ILs) offer tunable properties for diverse applications. This review explores their biological activities, drug delivery potential, and pharmaceutical applications, highlighting their promise in medicine and chemistry.
Area of Science:
- Chemistry
- Materials Science
- Biotechnology
- Pharmaceutical Sciences
Background:
- Ionic liquids (ILs) are ionic compounds with tunable properties.
- ILs are candidates for applications in extraction, synthesis, analytics, catalysis, biotechnology, therapeutics, and pharmaceutical sciences.
Purpose of the Study:
- Systematically review the classification, properties, and toxicity of ionic liquids.
- Explore the biological activity of ILs, including antimicrobial and anticancer properties.
- Emphasize the role of Active Pharmaceutical Ingredient-Ionic Liquids (API-ILs) in enhancing solubility and emulsification.
- Discuss the application of ILs in developing oral, transdermal, and topical drug delivery systems.
Main Methods:
- Literature review and systematic analysis of existing research on ionic liquids.
- Focus on biological activities, pharmaceutical applications, and drug delivery systems.
Main Results:
- Ionic liquids exhibit significant biological activities, including antimicrobial and anticancer properties.
- API-ILs demonstrate potential for improving drug solubility and emulsification.
- ILs are effective in developing various drug delivery systems (oral, transdermal, topical).
Conclusions:
- Ionic liquids possess exceptional potential in medicine, biology, and chemistry.
- ILs offer versatile applications in drug development and delivery.
- Further research into ILs can advance pharmaceutical and biotechnological fields.
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