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Updated: Jan 2, 2026

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots
Published on: May 21, 2013
[HYBRID OSTEOCHONDRAL TRANSPLANTATION - A NEW METHOD FOR SURGICAL TREATMENT OF OSTEOCHONDRITIS DISSECANS OF THE KNEE
G Lazishvili1, K Egiazarian1, A Ratjev1
1Pirogov Medical University, department of traumatology and orthopedy, Russia.
Abstract:
Knee osteochondritis desiccans, or Koenig's disease, is commonly found in active young people engaged in manual labor, sports etc., i.e. socially active population. Today, we have a good number of surgical methods to treatment of this disorder; however, there is still much controversy about their application, and no single approach is considered to be the optimal one. Plus, high-quality biomaterials required for the intervention are sometimes unavailable. The analysis of the results of treatment of patients (spanning several years) proved urgency of the problem and highlighted the necessity to solve a number of related issues. This paper presents the optimal method for surgical correction of Koenig's disease - "hybrid osteochondral transplantation". Indications for surgical intervention are justified, the technique of the operation is described, recommendations are given based on the practical experience of the authors. An analysis of the use of this technique in 27 patients showed its high efficiency, which allows the authors to recommend it for widespread use in clinical practice.
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