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BIOACTIVE GLASS-CERAMIC COMPOSITION IN SURGICAL MANAGEMENT OF PERIODONTAL INTRABONY DEFECTS.
1O. Bogomolets National Medical University, Kyiv, Ukraine.
Georgian Medical News
|December 6, 2019
Summary
This study evaluated bioactive glass-ceramic composition (BGCC) for periodontal bone defects. BGCC showed comparable results to deproteinized bovine bone mineral (DBBM) but improved bone density and patient comfort.
Area of Science:
- Biomaterials Science
- Periodontology
- Regenerative Medicine
Background:
- Periodontal intrabony defects pose significant challenges in regenerative therapy.
- Novel bone graft materials are needed to improve clinical outcomes and patient recovery.
- Bioactive glass-ceramics (BGCC) incorporating antibacterial ions offer potential for infected bony defects.
Purpose of the Study:
- To assess the clinical and radiological efficacy of a novel bioactive glass-ceramic composition (BGCC) as a bone substitute for periodontal intrabony defects.
- To compare BGCC with deproteinized bovine bone mineral (DBBM) and a collagen membrane in a controlled clinical study.
- To evaluate parameters including pocket probing depth (PPD), clinical attachment level (CAL), bone fill, and bone density.
Main Methods:
- A controlled clinical study involving 47 patients with periodontitis and 56 intrabony defects.
- Surgical intervention using BGCC with a collagen membrane in one group and DBBM with a collagen membrane in the control group.
- Evaluation of clinical and radiological parameters one year post-surgery, including PPD, CAL, EHI, and bone density.
Main Results:
- Both BGCC and DBBM groups showed significant reductions in PPD and gains in CAL, with no statistically significant difference between groups.
- Radiological evaluation revealed a significant increase in bone density in sites treated with BGCC compared to DBBM.
- The BGCC group demonstrated a trend towards reduced patient discomfort and improved early wound healing (EHI).
Conclusions:
- Bioactive glass-ceramic composition (BGCC) is effective in treating periodontal intrabony defects, offering comparable clinical outcomes to DBBM.
- BGCC demonstrates a significant advantage in enhancing bone density and shows potential for improved patient comfort and wound healing.
- Further long-term clinical studies with histological evaluation are warranted to fully elucidate the benefits of BGCC.
