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Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina
Published on: May 6, 2015
Postmitotic Cone Migration Mechanisms in the Mammalian Retina
Livia S Carvalho1, Carla B Mellough2
1University of Western Australia/Lions Eye Institute, Nedlands, WA, Australia. liviacarvalho@lei.org.au.
Abstract:
High visual acuity and the ability to identify colours is solely dependent upon healthy cone photoreceptors in the retina. Little is known about cone migration mechanisms during postmitotic retinal maturation which, if it occurs erroneously, can result in non-functional cells and altered vision. This review provides an overview of neuronal and cone somal migration mechanisms and the potential molecular partners and nuclear structures driving this process. Furthermore, it will also review foveal formation and how that differs from peripheral cone migration in the human retina.
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