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CCL7 Signaling in the Tumor Microenvironment.

Yeo Song Lee1, Yong Beom Cho2,3

  • 1Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Advances in Experimental Medicine and Biology
|February 16, 2020
PubMed
Summary

Chemokine (C-C motif) ligand 7 (CCL7) is highly expressed in various cancers. This review explores CCL7's role in immune cell recruitment and stromal biology, impacting cancer immunity and progression.

Keywords:
Antitumor effectCCL7CCRsCancer-associated adipocytesCancer-associated fibroblastClinical trialsCombination treatmentImmune cell infiltrationImmunotherapyMetastasisPro-tumor effectPrognosisProliferationTumor microenvironmentTumor-associated macrophage

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