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Updated: Dec 26, 2025

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Method for Obtaining Primary Ovarian Cancer Cells From Solid Specimens
Published on: February 4, 2014
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Pure Primary Ovarian Carcinoid Tumor
Tracy S Halvorson1, Robert A Robinson, Megan I Samuelson
1Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Summary
Pure primary ovarian carcinoid tumors (PPOCTs) are rare, solid ovarian masses. This case report details a PPOCT diagnosis, highlighting its unique characteristics and metastatic potential in a middle-aged woman.
Area of Science:
- Gynecologic Oncology
- Pathology
- Surgical Oncology
Background:
- Primary ovarian carcinoid tumors (PPOCTs) are rare, typically arising within mature cystic teratomas.
- Pure PPOCTs are exceptionally uncommon, defined by the absence of teratomatous or other neoplastic elements.
Observation:
- A middle-aged woman presented with a large (20 cm) abdominopelvic mass.
- Imaging revealed a significant solid mass requiring surgical intervention.
Findings:
- Surgical resection yielded a large, solid, yellow-tan ovarian mass diagnosed as a PPOCT.
- Histopathological examination confirmed the PPOCT diagnosis and identified para-aortic lymph node metastases.
Implications:
- This case underscores the importance of recognizing the distinct gross and microscopic features of PPOCTs.
- It also emphasizes the need to consider PPOCTs in the differential diagnosis of solid ovarian masses, particularly regarding intraoperative evaluation and metastatic potential.

