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Nonsteroidal Antiinflammatory Drugs for Acute and Chronic Pain
Timothy J Atkinson1, Jeffrey Fudin2
1Pain Management, PGY2 Pain Management & Palliative Care Pharmacy Residency, VA Tennessee Valley Healthcare System, 3400 Lebanon Pike, Murfreesboro, TN 37129, USA.
Summary
Nonsteroidal anti-inflammatory drugs (NSAIDs) significantly impact rheumatic and arthritic conditions by reducing inflammation and improving mobility. However, their widespread and often inappropriate use necessitates careful monitoring to mitigate serious adverse effects.
Area of Science:
- Rheumatology
- Pharmacology
- Internal Medicine
Background:
- Nonsteroidal anti-inflammatory drugs (NSAIDs) are crucial in managing rheumatic and arthritic conditions.
- Their benefits include reducing inflammation, stiffness, and improving joint mobility.
- NSAID use is prevalent, exceeding opioid use, with significant concerns regarding inappropriate utilization.
Purpose of the Study:
- To underscore the critical importance of understanding NSAID use and its impact on rheumatic and arthritic diseases.
- To highlight the need for balancing NSAID benefits against their potential serious adverse effects.
- To advocate for evidence-based and individualized NSAID discontinuation protocols.
Main Methods:
- This study is a review of current literature on NSAID use in rheumatic and arthritic conditions.
- Analysis of the impact of NSAIDs on inflammation, stiffness, and mobility.
- Assessment of NSAID usage patterns and associated risks.
Main Results:
- NSAIDs offer significant therapeutic benefits for connective tissue disorders.
- Inappropriate NSAID use is a widespread issue.
- The risks associated with NSAID use require careful monitoring and understanding.
Conclusions:
- NSAID use is fundamental in treating rheumatic and arthritic conditions, offering substantial benefits.
- Mitigating risks necessitates vigilant monitoring of NSAID use and its effects.
- Discontinuation of NSAIDs must be guided by evidence and tailored to individual patient needs.
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