[Rubor, calor, dolor, tumor: skin and soft tissue infections]

Eleftheria Kampouri1, Paraskevas Filippidis1, Loïc Lhopitallier1

  • 1Service des maladies infectieuses, CHUV, 1011 Lausanne.

Revue Medicale Suisse
|April 18, 2020
PubMed

Insights

Diagnosing skin infections can be difficult, requiring empiric antibiotics for common bacteria like streptococci and Staphylococcus aureus. Early surgery and antibiotics are crucial for severe necrotizing fasciitis (NF).

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Microbiology

Background:

  • Skin infections are common but challenging to diagnose accurately.
  • Microbiological documentation is often lacking, necessitating empiric antibiotic choices.
  • Necrotizing fasciitis (NF) is a severe, rare infection requiring prompt intervention.

Purpose of the Study:

  • To review the key aspects of diagnosing and treating common skin infections.
  • To highlight the importance of empiric antibiotic coverage for prevalent bacteria.
  • To discuss the management of severe infections like necrotizing fasciitis.

Main Methods:

  • Literature review of diagnostic and treatment strategies for skin infections.
  • Analysis of common bacterial pathogens and appropriate antibiotic regimens.
  • Discussion of surgical and medical management of necrotizing fasciitis.

Main Results:

  • Empiric antibiotics should target streptococci and Staphylococcus aureus.
  • Consideration of alternative pathogens is necessary for immunocompromised patients or specific exposures.
  • Early surgical debridement alongside antibiotics is critical for necrotizing fasciitis.

Conclusions:

  • Optimal treatment duration, recurrence prevention, and immunoglobulin use for NF remain areas for further research.
  • Accurate diagnosis and timely, appropriate treatment are essential for managing skin infections.
  • This review synthesizes current knowledge on skin infection diagnosis and treatment.

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