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[Rubor, calor, dolor, tumor : skin and soft tissue infections]
Eleftheria Kampouri1, Paraskevas Filippidis1, Loïc Lhopitallier1
1Service des maladies infectieuses, CHUV, 1011 Lausanne.
Abstract:
Skin infections are a frequent cause of consultation, yet the diagnosis can be challenging for physicians. Microbiological documentation is rare, and empiric antibiotic regimens should cover the most commonly identified bacteria, i.e. streptococci Staphylococcus aureus. Other pathogens should be considered in case of immunosuppression or certain exposures. Necrotizing fasciitis (NF) is a severe but rare infection. Early surgical management in parallel with antibiotics is the cornerstone of treatment. Despite the high incidence of these infections, little progress has been made in their management and some areas of uncertainty exist, especially regarding the optimal duration of treatment, the prevention of recurrences and the use of polyclonal immunoglobulins for NF. This article reviews the main aspects of diagnosis and treatment of these infections.
Insights
Diagnosing skin infections can be difficult, requiring empiric antibiotics for common bacteria like streptococci and Staphylococcus aureus. Early surgery and antibiotics are crucial for severe necrotizing fasciitis (NF).
Area of Science:
- Dermatology
- Infectious Diseases
- Microbiology
Background:
- Skin infections are common but challenging to diagnose accurately.
- Microbiological documentation is often lacking, necessitating empiric antibiotic choices.
- Necrotizing fasciitis (NF) is a severe, rare infection requiring prompt intervention.
Purpose of the Study:
- To review the key aspects of diagnosing and treating common skin infections.
- To highlight the importance of empiric antibiotic coverage for prevalent bacteria.
- To discuss the management of severe infections like necrotizing fasciitis.
Main Methods:
- Literature review of diagnostic and treatment strategies for skin infections.
- Analysis of common bacterial pathogens and appropriate antibiotic regimens.
- Discussion of surgical and medical management of necrotizing fasciitis.
Main Results:
- Empiric antibiotics should target streptococci and Staphylococcus aureus.
- Consideration of alternative pathogens is necessary for immunocompromised patients or specific exposures.
- Early surgical debridement alongside antibiotics is critical for necrotizing fasciitis.
Conclusions:
- Optimal treatment duration, recurrence prevention, and immunoglobulin use for NF remain areas for further research.
- Accurate diagnosis and timely, appropriate treatment are essential for managing skin infections.
- This review synthesizes current knowledge on skin infection diagnosis and treatment.
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