Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gradient and Del Operator01:14

Gradient and Del Operator

4.2K
In mathematics and physics, the gradient and del operator are fundamental concepts used to describe the behavior of functions and fields in space. The gradient is a mathematical operator that gives both the magnitude and direction of the maximum spatial rate of change. Consider a person standing on a mountain. The slope of the mountain at any given point is not defined unless it is quantified in a particular direction. For this reason, a "directional derivative" is defined, which is a vector...
4.2K
Extraction: Partition and Distribution Coefficients01:14

Extraction: Partition and Distribution Coefficients

4.5K
The distribution law or Nernst's distribution law is the law that governs the distribution of a solute between two immiscible solvents. This law, also known as the partition law, states that if a solute is added to the mixture of two immiscible solvents at a constant temperature, the solute is distributed between the two solvents in such a way that the ratio of solute concentrations in the solvents remains constant at equilibrium.
For extracting a solute from an aqueous phase into an...
4.5K
Second Derivatives and Laplace Operator01:22

Second Derivatives and Laplace Operator

2.5K
The first order operators using the del operator include the gradient, divergence and curl. Certain combinations of first order operators on a scalar or vector function yield second order expressions. Second-order expressions play a very important role in mathematics and physics. Some second order expressions include the divergence and curl of a gradient function, the divergence and curl of a curl function, and the gradient of a divergence function.
Consider a scalar function. The curl of its...
2.5K
Reducing Line Loss01:18

Reducing Line Loss

300
In a three-phase circuit, line loss is an indicator of energy dissipated as heat due to the resistance of transmission lines. To address this, incorporating transformers into the system—a step-up transformer at the source and a step-down transformer at the load—is a strategic solution. Two three-phase transformers are introduced to improve this.
With a step-up transformer at the source, the voltage is increased, thereby reducing the current in the transmission lines since power loss in...
300
Vector Operations01:20

Vector Operations

1.8K
Vectors are physical quantities that have both magnitude and direction. The vector operations include addition, subtraction, and scalar multiplication.
A vector multiplied by a scalar value is called scalar multiplication. The result obtained is a new vector with a different magnitude. If the scalar is positive, the direction of the vector remains the same, but if it is negative, the direction of the vector is reversed. For example, the product of the mass and velocity yields the momentum.
1.8K
Linear Approximation in Frequency Domain01:26

Linear Approximation in Frequency Domain

307
Linear systems are characterized by two main properties: superposition and homogeneity. Superposition allows the response to multiple inputs to be the sum of the responses to each individual input. Homogeneity ensures that scaling an input by a scalar results in the response being scaled by the same scalar.
In contrast, nonlinear systems do not inherently possess these properties. However, for small deviations around an operating point, a nonlinear system can often be approximated as linear....
307

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An FPGA-Based Event-Timing Front-End for Time-Resolved Sensing with Dual-Mode Experimental Characterization.

Sensors (Basel, Switzerland)·2026
Same author

A Fully Integrated, Power-Efficient, 0.07-2.08 mA, High-Voltage Neural Stimulator in a Standard CMOS Process.

Sensors (Basel, Switzerland)·2022
Same author

Architecture-Level Optimization on Digital Silicon Photomultipliers for Medical Imaging.

Sensors (Basel, Switzerland)·2022
Same author

A 32-Channel Time-Multiplexed Artifact-Aware Neural Recording System.

IEEE transactions on biomedical circuits and systems·2021
Same author

Recording Strategies for High Channel Count, Densely Spaced Microelectrode Arrays.

Frontiers in neuroscience·2021
Same author

A Low-Resources TDC for Multi-Channel Direct ToF Readout Based on a 28-nm FPGA.

Sensors (Basel, Switzerland)·2021
Same journal

Multiplexed Crossbar GFET Array With BioADC for Multi-Modal Aptamer-Based Sensing.

IEEE transactions on biomedical circuits and systems·2026
Same journal

A VPG-Based Adaptive Windowing PPG Sensor IC for Low-Power Wearable Monitoring.

IEEE transactions on biomedical circuits and systems·2026
Same journal

A Chopper Amplifier with Feedforward SAR ADC Assisted DC Servo Loop Achieving ±1V DC Offset Cancellation in 2.1s for Neural Signal Recordings.

IEEE transactions on biomedical circuits and systems·2026
Same journal

ANP-R: A 22nm 0.88pJ/SOP Asynchronous SNN-based Processor with Coarse-Grained Reconfigurable Architecture Enabling Multisensory On-chip Incremental Learning for Edge AI.

IEEE transactions on biomedical circuits and systems·2026
Same journal

A High-Efficiency Neural Processing SoC for Adaptive Closed-Loop Neuromodulation.

IEEE transactions on biomedical circuits and systems·2026
Same journal

DustNet: A Wireless Network of Ultrasonic Neural Implants.

IEEE transactions on biomedical circuits and systems·2026
See all related articles

Related Experiment Video

Updated: Dec 23, 2025

Author Spotlight: Revolutionizing Remote Surgery with Augmented Reality and Robotics for Enhanced Precision and Accessibility
07:46

Author Spotlight: Revolutionizing Remote Surgery with Augmented Reality and Robotics for Enhanced Precision and Accessibility

Published on: August 9, 2024

1.1K

Charge-Redistribution Based Quadratic Operators for Neural Feature Extraction.

Rafaella Fiorelli, Manuel Delgado-Restituto, Angel Rodriguez-Vazquez

    IEEE Transactions on Biomedical Circuits and Systems
    |April 20, 2020
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a novel mixed-signal multiplier using a SAR converter for neural signal feature extraction. The developed chips efficiently detect action potentials and compute energy, outperforming prior work in area-time-power efficiency.

    More Related Videos

    Author Spotlight: Enhancement of Salient Object Detection for Smart Grid Applications
    03:31

    Author Spotlight: Enhancement of Salient Object Detection for Smart Grid Applications

    Published on: December 15, 2023

    931

    Related Experiment Videos

    Last Updated: Dec 23, 2025

    Author Spotlight: Revolutionizing Remote Surgery with Augmented Reality and Robotics for Enhanced Precision and Accessibility
    07:46

    Author Spotlight: Revolutionizing Remote Surgery with Augmented Reality and Robotics for Enhanced Precision and Accessibility

    Published on: August 9, 2024

    1.1K
    Author Spotlight: Enhancement of Salient Object Detection for Smart Grid Applications
    03:31

    Author Spotlight: Enhancement of Salient Object Detection for Smart Grid Applications

    Published on: December 15, 2023

    931

    Area of Science:

    • Mixed-signal integrated circuit design
    • Neural signal processing
    • Biomedical engineering

    Background:

    • Feature extraction is crucial for analyzing neural signals.
    • Quadratic operators are effective for characterizing neural activity.
    • Existing methods often require significant power and area.

    Purpose of the Study:

    • To propose a SAR converter-based mixed-signal multiplier architecture.
    • To implement and evaluate two quadratic operators (MAE and NEO) for neural signal analysis.
    • To demonstrate energy computation and action potential detection capabilities.

    Main Methods:

    • Designed a mixed-signal multiplier architecture utilizing a SAR converter.
    • Implemented programmable chips for Moving Average Energy (MAE) and Nonlinear Energy Operator (NEO).
    • Fabricated prototypes in a HV-180 nm CMOS process.

    Main Results:

    • Experimental results validate the suitability of MAE and NEO for energy computation and action potential detection.
    • Prototypes achieved low power consumption: 116 nW for MAE and 178 nW for NEO at 30 kS/s.
    • The design digitizes both input neural signals and operator outputs without requiring digital multipliers.

    Conclusions:

    • The proposed SAR converter-based mixed-signal multiplier offers efficient neural signal feature extraction.
    • The implemented MAE and NEO operators demonstrate superior area×power performance compared to existing solutions.
    • This architecture is promising for low-power, high-performance neural signal processing applications.