Related Experiment Video
Updated: Dec 23, 2025

Manual Restraint and Common Compound Administration Routes in Mice and Rats
Published on: September 26, 2012
Physical and Chemical Restraints (an Update)
Pilar Guerrero1, Mark B Mycyk1
1Department of Emergency Medicine, Cook County Health, 1950 West Polk, 7th Floor EM Admin, Chicago, IL 60612, USA.
Abstract:
Violent, combative and intoxicated patients are a common problem in the emergency department, and the emergency physician must be prepared to control the situation safely and effectively when a patient begins to exhibit dangerous behavior. This article reviews initial de-escalation techniques to reduce the need for patient restraint. It then details the 2 types of restraints (physical and chemical) and the clear indications for each type. The high-risk nature of utilization of restraints is reviewed, as well as the means by which to ensure patient and staff safety and decrease adverse outcomes.
Related Concept Videos
Specialized Care Centers and Settings-II
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...
Retarders
The function of retarders is to delay the setting of concrete, and this effect can be measured using a penetration test. The retardation process involves adding...
Drug Therapy
Antianxiety Medications
CNS Depressants: Barbiturates and Benzodiazepines
Spasmolytic Agents: Chemical Classification
A major class of centrally acting spasmolytics is the α2-agonist, such as tizanidine. These drugs bind to α2-adrenoceptors, inhibiting the release of the excitatory neurotransmitter glutamate. They also...
Physical and Chemical Properties of Matter

