Related Experiment Video
Updated: Dec 20, 2025

Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
Pediatric Procedural Sedation in the Emergency Setting
Elizabeth A Lucich1,2, Nicholas S Adams1,2, Paige C Goote3
1Michigan State University College of Human Medicine, Grand Rapids, Mich.
Insights
Procedural sedation in pediatric emergency departments is generally safe. While longer sedation times slightly increase complication risk, no specific duration showed a significant increase in adverse events.
Area of Science:
- Pediatric Emergency Medicine
- Anesthesiology
- Patient Safety
Background:
- Pediatric emergency department visits frequently involve procedures requiring sedation.
- Adverse events associated with pediatric procedural sedation are well-researched, but sedation duration's impact is less understood.
Purpose of the Study:
- To determine the complication rate and severity of pediatric procedural sedation.
- To investigate the correlation between sedation duration and the risk of complications.
Main Methods:
- Retrospective study of 1,814 pediatric patients receiving sedation from August 2011 to August 2016.
- Analysis included patient demographics, procedure type, sedation details, and complications.
- Logistic regression assessed risk factors, with sedation time as a key variable.
Main Results:
- The overall complication rate was 3.9% (70 patients).
- Median sedation time was 20 minutes.
- Sedation time was a significant predictor of complications (OR: 1.021; 95% CI, 1.004-1.039), even after controlling for other factors.
Conclusions:
- Procedural sedation in pediatric emergency departments is safe.
- Longer procedural sedations show a slight increase in risk, but no specific duration significantly elevates complication risk.
- The study supports the continued safe use of procedural sedation in pediatric EDs.
Background:
Pediatric emergency department (ED) visits are common. Many are due to injury, which require procedural treatments with sedation. There are many well researched independent predictors of adverse events for pediatric procedural sedation. The duration of sedation as a predictor of adverse events has not been well studied. This study aims to determine the complication rate and severity of procedural sedation as well as determine if the duration of sedation is correlated with an increased risk of complications.
Methods:
After Institutional Review Board approval, a retrospective study was performed on all patients seen at Helen Devos Children's ED who received sedation from August 1, 2011, to August 15, 2016. Study variables included age, weight, type of procedure, American Society of Anesthesiologist (ASA) physical status class, Mallampati score, comorbidities, sedation medication, sedation time, and complication. A logistic regression was performed assessing risk factors for complications. Statistical significance was assessed at P < 0.05.
Results:
There were 1,814 patients included in the study. Median sedation time was 20 minutes. There were 70 (3.9%) total complications. Controlling for age, weight, comorbidities, ASA class, Mallampati score, and total sedation medication, sedation time was a significant predictor of a complication (odds ratio: 1.021; 95% CI, 1.004-1.039).
Conclusions:
Pediatric patients can safely undergo procedural sedation in the ED. This study demonstrates a high safety profile for long procedural sedations with slight increases in risk as sedation time increases. There is no identifiable time where the duration of sedation significantly increases the risk of complication.
More Related Videos
Related Concept Videos
Parenteral Anesthetics: Overview
Stages of General Anesthesia
Drug Delivery: Enteral Route
Inhalational Anesthetics: Overview
Drug Dosing: Infants and Children
Depolarizing Blockers: Pharmocokinetics

