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Protein conformational changes affect the sodium triple-quantum MR signal.

Dennis Kleimaier1, Victor Schepkin2, Ruomin Hu1

  • 1Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany.

NMR in Biomedicine
|July 14, 2020
PubMed
Summary

Sodium triple-quantum (TQ) signals are sensitive to pH and protein unfolding. Changes in these factors significantly alter TQ signals, impacting their use as biomarkers in biological systems.

Keywords:
bovine serum albuminelectric quadrupole interactionprotein foldingsodium NMRsodium triple-quantum signaltriple-quantum time proportional phase increment

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