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Weight Reduction by the Low-Insulin-Method-A Randomized Controlled Trial.

Martin Röhling¹, Katharina Martin², Sabine Ellinger²

¹West-German Centre of Diabetes and Health, Dusseldorf Catholic Hospital Group, 40591 Dusseldorf, Germany.

|October 3, 2020

Summary

This summary is machine-generated.

The Low-Insulin-Method within the SAMMAS program effectively reduces weight in overweight individuals. This occupational health intervention supports significant and sustained weight loss, improving overall health markers.

Keywords:

RCT meal replacement therapy telemedical coaching weight loss

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Area of Science:

Metabolic Health
Obesity Research
Occupational Health

Background:

Continuous high insulin levels are linked to weight gain and cardiometabolic diseases.
Overweight and obesity require effective, long-term weight management strategies.

Purpose of the Study:

To evaluate the efficacy of the Low-Insulin-Method integrated into the SHAPE-AND-MOTION-Medical-Accompanied-Slimming (SAMMAS) program for weight reduction.
To assess the impact of the intervention on metabolic health markers and long-term weight maintenance.

Main Methods:

A randomized controlled trial comparing an intervention group (SI) with a waiting list control group (WL).
The SAMMAS program included group seminars, low-carbohydrate nutrition (with formula diet), continuous glucose monitoring, telemetric monitoring, and telemedical coaching.
Intention-to-treat analyses were conducted at 12, 26, and 52 weeks.

Main Results:

The intervention group achieved a significant weight reduction of -6.3 kg after 12 weeks (p < 0.001).
Improvements were observed in fasting blood glucose, HbA1c, quality of life, fasting insulin, blood pressure, and eating behavior (p < 0.05).
Weight reduction was maintained at 26 and 52 weeks (-6.7 kg and -6.1 kg, respectively).

Conclusions:

The SAMMAS program, utilizing the Low-Insulin-Method, is effective for clinically relevant weight reduction in overweight and obese individuals.
The intervention promotes sustained weight loss and improves multiple health parameters.
This occupational healthcare program offers a viable solution for long-term weight management.