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[Intracranial meningioma of an infant: a case report]
H Kimura1, K Nakagawa, S Sakaki
1Department of Neurosurgery, Ehime University School of Medicine, Japan.
Insights
Intracranial meningiomas are exceptionally rare in infants under one year old. This case highlights a male infant with a benign fibroblastic meningioma, emphasizing unique characteristics compared to adult tumors.
Area of Science:
- Pediatric Neurosurgery
- Neuro-oncology
- Infant Pathology
Background:
- Intracranial meningiomas in infants under one year are exceedingly rare, with only 22 prior reported cases.
- This study presents a case of an 11-month-old male infant diagnosed with an intracranial meningioma.
Observation:
- The infant presented with seizures and unconsciousness, with CT scans revealing a frontal lobe lesion.
- The tumor, measuring 3x3x3 cm and weighing 10g, was surgically removed en bloc.
- Histological examination confirmed a fibroblastic meningioma, a benign subtype.
Findings:
- Review of literature revealed distinct features in infant meningiomas: male predominance (16/23), supratentorial location, frequent lack of dural attachment (8/18), and common cyst formation (9/16).
- The majority of infant meningiomas are histologically benign (17/22), with fibroblastic type being most common (15/22).
Implications:
- Understanding these unique infantile meningioma characteristics is crucial for diagnosis and treatment planning.
- This case contributes to the limited knowledge base, aiding in the management of rare pediatric brain tumors.
Abstract:
An 11-month-old male infant with intracranial meningioma is presented. Intracranial meningiomas in infancy under the age of 1 year are extremely rare, and only 22 cases have been reported previously. The authors reviewed the clinical and pathological findings of these meningiomas including our case. The patient feel ill with convulsive attacks followed by unconsciousness at 11 months of age without any other neurological deficit. Computed tomographic scannings revealed a high density lesion in the frontal region. The tumor was located entirely in the frontal lobe 2 cm anterior to the Sylvian vein and was removed en bloc. It was 3 X 3 X 3 cm in diameter and 10 g in weight. Histological diagnosis was of fibroblastic meningioma. He was discharged two weeks after the operation without any neurological deficits. Several characteristic features of meningiomas in infant under 1 year old were drawn from the review of literature in comparison with those of meningiomas in adult. 1) Predominant sex was male (16/23). 2) All meningiomas developed in the supra-tentorium. 3) Eight of 18 tumors being described did not have the dural attachment. 4) Nine of 16 tumors showed cyst formation. 5) The most cases were histologically diagnosed benign (17 of 22), and 15 cases was fibroblastic meningioma.