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Updated: Dec 1, 2025

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
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Determining if Reaction Selectivity Can Be Controlled by the H/D Isotope Effect in CH···O Interactions

Haruki Funahashi1, Masanori Tachikawa2, Taro Udagawa1

  • 1Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, Yanagido 1-1, Gifu 501-1193, Japan.

Organic Letters
|November 10, 2020
PubMed
Summary

The H/D isotope effect in CH···O interactions was studied. Deuterium substitution showed a negligible impact, suggesting it cannot control reaction selectivity in these specific interactions.

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