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Updated: Nov 29, 2025

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
Published on: August 12, 2019
Functional Mapping for Glioma Surgery, Part 2: Intraoperative Mapping Tools.
Ramin A Morshed1, Jacob S Young1, Anthony T Lee1
1Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.
Intraoperative functional mapping helps surgeons avoid permanent neurological damage and remove more tumor. This review covers motor, language, and cognitive mapping techniques, including awake mapping and complication avoidance strategies.
Area of Science:
- Neurosurgery
- Neuroscience
- Cognitive Science
Background:
- Intraoperative functional mapping is crucial for neurosurgery.
- It aims to prevent permanent neurological deficits and maximize tumor resection.
- Assessing motor, language, and cognitive functions during surgery is vital.
Purpose of the Study:
- To describe techniques for intraoperative motor and language mapping.
- To discuss awake mapping and novel cognitive testing paradigms.
- To review complications and strategies for their avoidance.
Main Methods:
- Review of established and novel intraoperative mapping techniques.
- Inclusion of awake mapping considerations.
- Discussion of cognitive assessment paradigms and complication management.
Main Results:
- Detailed description of motor and language mapping procedures.
- Exploration of less traditional cognitive testing methods.
- Identification of potential complications and preventative measures.
Conclusions:
- Intraoperative mapping is essential for safe and effective tumor resection.
- A comprehensive understanding of mapping techniques improves patient outcomes.
- Awareness and management of complications are key to successful mapping.

