Interleukin (IL)-24: Reconfiguring the Tumor Microenvironment for Eliciting Antitumor Response

Rajagopal Ramesh1,2,3, Rebaz Ahmed4,5, Anupama Munshi6,7

  • 1Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. rajagopal-ramesh@ouhsc.edu.

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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