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Updated: Nov 6, 2025
Ultrasound-based Pulse Wave Velocity Evaluation in Mice
Published on: February 14, 2017
On the Feasibility of Pulse Wave Velocity Imaging for Remote Assessment of Physiological Functions
Gennadi Saiko1, M Dervenis2, A Douplik2,3
1Swift Medical Inc., Toronto, ON, Canada. Gennadi.saiko@swiftmedical.com.
Introduction:
Pulse wave velocity imaging (PWVi) is a novel technology developed by our group for real-time assessment of ischemia. The objectives of this proof-of-concept study included (1) remote detection of blood flow pulse and (2) assessing the feasibility of pulse wave velocity (PWV) imaging.
Methods:
PWVi is based on a 12-bit RGB camera (Basler acA-2000-165uc) capturing videos at up to 1000 fps. Videos of the hands of healthy individuals were taken, segmented, and processed to assess pulse wave velocity (PWV) and photoplethysmographic (PPG) signals.
Results:
PWV and PPG waveforms were readily collected for multiple segments. The PWVi device performed well, even without an external source of illumination. Mean PWV of 341.3 (±151.0) cm/s was obtained.
Conclusions:
PWVi is a portable, accessible, and cost-effective technology for assessing physiological parameters remotely.
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