High-Risk Population Based on BC Risk Factors

Area of Science:

• Oncology
• Epidemiology
• Public Health

Background:

• Breast cancer (BC) is a significant global health concern, ranking as the second leading cause of female cancers worldwide.
• While Western countries have observed declining BC incidence and mortality rates, Asian populations are experiencing a rapid increase.
• These epidemiological shifts are influenced by medical advancements, public health policies, and evolving population risk factors.

Purpose of the Study:

• To review the epidemiological characteristics of breast cancer globally.
• To summarize identified risk factors associated with breast cancer development.
• To explore the potential for risk modification in populations at high risk for breast cancer.

Main Methods:

• Literature review of epidemiological studies on breast cancer.
• Analysis of secular trends in breast cancer incidence and mortality rates.
• Synthesis of research on various breast cancer risk factors and their impact.

Main Results:

• Significant divergence in breast cancer trends between Western and Asian populations noted.
• Identification of key epidemiological characteristics and risk factors contributing to breast cancer.
• Exploration of strategies for mitigating breast cancer risk in susceptible groups.

Conclusions:

• Understanding global epidemiological variations is crucial for targeted breast cancer prevention and control.
• Modifiable risk factors present opportunities for intervention in high-risk populations.
• Continued research into breast cancer etiology and prevention is essential for reducing global burden.