Related Experiment Video
Updated: Nov 4, 2025

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
Published on: March 3, 2021
Hypothermia for Acute Spinal Cord Injury
Aditya Vedantam1, Allan D Levi1
1Department of Neurological Surgery, University of Miami MILLER School of Medicine, Lois Pope Life Center, 1095 Northwest 14th Terrace, Suite 2-24, Miami, FL 33136, USA.
Abstract:
Neuroprotection after acute spinal cord injury is an important strategy to limit secondary injury. Animal studies have shown that systemic hypothermia is an effective neuroprotective strategy that can be combined with other therapies. Systemic hypothermia affects several processes at the cellular level to reduce metabolic activity, oxidative stress, and apoptotic neuronal cell death. Modest systemic hypothermia has been shown to be safe and feasible in the acute phase after cervical spinal cord injury. These data have provided the impetus for an active multicenter randomized controlled trial for modest systemic hypothermia in acute cervical spinal cord injury.
More Related Videos
06:43Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
Published on: November 21, 2017
06:51Development of an Algorithm to Perform a Comprehensive Study of Autonomic Dysreflexia in Animals with High Spinal Cord Injury Using a Telemetry Device
Published on: July 29, 2016
Related Concept Videos
Decreased Body Temperature
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Cardiopulmonary Resuscitation IV: Pharmacological Management
Increased Body Temperature