Aggregation-Induced Emission Materials that Aid in Pharmaceutical Research

Area of Science:

• Materials Science
• Pharmaceutical Sciences
• Biomedical Engineering

Background:

• In situ visualization of drugs is crucial for understanding pharmacokinetics and mechanisms.
• Aggregation-induced emission (AIE) materials possess unique fluorescence properties, biocompatibility, and sensitivity, making them suitable for pharmaceutical research.

Purpose of the Study:

• To review the progress of AIE materials in pharmaceutical research.
• To discuss the applications of AIE materials in drug delivery, prodrugs, and theranostics.
• To explore the future opportunities and challenges of AIE materials in pharmacology.

Main Methods:

• Literature review of AIE materials in pharmaceutical applications.
• Discussion of AIE carriers for drug delivery systems.
• Analysis of AIE multifunctional prodrugs and theranostic agents.

Main Results:

• AIE materials are increasingly utilized for drug visualization due to their superior fluorescence.
• Applications include AIE-based drug carriers, multifunctional prodrugs, and theranostic agents.
• Significant advancements are noted in sensitivity and biocompatibility.

Conclusions:

• AIE materials offer versatile solutions for drug visualization and delivery.
• They hold substantial promise for advancing pharmacological research and clinical applications.
• Further research is needed to overcome challenges and fully realize their potential.