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Updated: Oct 18, 2025

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Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
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Alternative Access for Transcatheter Aortic Valve Replacement: A Comprehensive Review
Marvin H Eng1, Mohammed Qintar2, Dmitrios Apostolou3
1Division of Cardiology, Banner- University Medical Center Phoenix, 1111 East McDowell Road, Phoenix, AZ 85006, USA.
Interventional Cardiology Clinics
|October 1, 2021
Summary
Transfemoral access is common for transcatheter aortic valve replacement (TAVR), but alternative routes are necessary for many patients. This review explores these alternative TAVR access options, detailing their benefits and drawbacks.
Area of Science:
- Interventional Cardiology
- Cardiovascular Surgery
- Medical Device Technology
Background:
- Transfemoral access is the standard approach for transcatheter aortic valve replacement (TAVR).
- A significant percentage of patients (up to 21%) require alternative access methods for TAVR due to anatomical or clinical factors.
- Optimal patient selection and procedural success depend on understanding various access routes.
Purpose of the Study:
- To comprehensively review alternative access strategies for TAVR.
- To analyze the available data on different TAVR access routes.
- To present the advantages and disadvantages of each alternative access method.
Main Methods:
- Systematic literature review of studies on TAVR alternative access.
- Analysis of procedural outcomes, complications, and patient selection criteria.
- Comparative assessment of different access techniques.
Main Results:
- The review synthesizes data on various alternative TAVR access routes, including transfemoral, transaxillary, and others.
- Each access route presents unique benefits and challenges regarding feasibility, safety, and efficacy.
- Patient-specific factors significantly influence the choice of optimal TAVR access.
Conclusions:
- Alternative access routes are crucial for expanding TAVR eligibility.
- A thorough understanding of pros and cons for each access method is vital for procedural planning.
- Further research may refine patient selection and optimize outcomes for alternative TAVR access.
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