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Updated: Oct 18, 2025

A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters
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A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters

Published on: April 20, 2015

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Cation-coupled chloride cotransporters: chemical insights and disease implications

Corinne Portioli1,2, Manuel José Ruiz Munevar2, Marco De Vivo2

  • 1Brain Development and Disease Laboratory, Istituto Italiano di Tecnologia (IIT), Via Morego 30, 16163 Genoa, Italy.

Trends in Chemistry
|October 4, 2021
PubMed

Keywords:
CCC physiologycryo-EMion-binding sitesmembrane transportersselective drugsstructural biology

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