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Copper-Mediated Decarboxylative Coupling between Arylacetic Acids and 1,3-Dicarbonyl Compounds

Yinrong Wu1, Kangmei Wen1, Jiewen Chen1

  • 1Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, 1023 South Shatai Road, Baiyun District, Guangzhou 510515, PR China.

Organic Letters
|October 6, 2021
PubMed
Summary

A novel copper-catalyzed reaction efficiently couples arylacetic acids with 1,3-dicarbonyl compounds. Some products showed significant anticancer activity in cell line studies.

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