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Updated: Oct 15, 2025

11:44
Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities
Published on: October 2, 2018
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Synthesis, self-aggregation and cryopreservation effects of perylene bisimide-glycopeptide conjugates
Abstract:
Three perylene bisimide-glycopeptide conjugates (PBI-AFF-Man, PBI-AFF-Glu and PBI-AFF-Gal) were synthesized, which showed moderate activity in the control of ice crystal growth. Furthermore, the cellular cryopreservation effects of PBI-AFF-Man, PBI-AFF-Glu and PBI-AFF-Gal showed enhancements in cell viabilities, especially for PBI-AFF-Glu with values of 22.77 ± 3.33% (HeLa cells), 19.43 ± 1.90% (A549 cells) and 16.63 ± 1.76% (GES-1 cells) at a dose of 1.0 mg mL-1. This work will help guide the development of self-assembled cryoprotectants.

