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Updated: Oct 9, 2025

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
Published on: November 22, 2014
Novel Approaches in Biomolecule Labeling.
1Normandie University, CNRS, UNIROUEN, INSA Rouen, COBRA, 76000 Rouen, France.
Selective functionalization of biomolecules like proteins and nucleic acids is key for chemical biology research and biomedical applications. This enables advancements in diagnostics and targeted therapies.
Area of Science:
- Bioconjugation Chemistry
- Chemical Biology
- Biomedical Research
Background:
- Selective modification of biomolecules is crucial for understanding biological systems.
- Applications span from basic research to advanced diagnostics and therapeutics.
Discussion:
- Challenges in achieving precise biomolecule functionalization.
- Exploring novel chemical strategies for targeted modification.
Key Insights:
- Advancements in selective protein, nucleic acid, lipid, and carbohydrate functionalization.
- Enabling precise control over molecular interactions and functions.
Outlook:
- Potential for developing next-generation diagnostics.
- Future directions in targeted drug delivery and personalized medicine.
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