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Updated: Oct 6, 2025

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Folding and Characterization of a Bio-responsive Robot from DNA Origami

Published on: December 3, 2015

Artificial Cells Based on DNA Nanotechnology.

Na Zhao¹, Yingzhi Chen¹, Gaoxian Chen¹

¹Department of Pharmacology and Chemical Biology, & Institute of Molecular Medicine, Shanghai Key Laboratory for Nucleic Acid Chemistry and Nanomedicine, Clinical and Fundamental Research Center, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

ACS Applied Bio Materials

|January 13, 2022

Summary

This summary is machine-generated.

DNA nanotechnology enables the creation of artificial cells that mimic cellular functions. These DNA-based nanostructures are used for protein mimicking, biosensing, and building signaling networks within cells.

Keywords:

DNA nanostructures DNA nanotechnology artificial cells bionic elements cellular microenvironment

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Last Updated: Oct 6, 2025

Folding and Characterization of a Bio-responsive Robot from DNA Origami

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Designing a Bio-responsive Robot from DNA Origami

Designing a Bio-responsive Robot from DNA Origami

Published on: July 8, 2013

Area of Science:

Synthetic Biology
Nanotechnology
Biochemistry

Background:

Artificial cells offer versatile platforms for studying biological processes.
DNA nanotechnology advancements facilitate the design of complex nanostructures.
Mimicking cellular components with DNA nanostructures is a growing field.

Purpose of the Study:

To review studies on artificial cells constructed using DNA nanotechnology.
To highlight the morphological and functional mimicry of membrane proteins.
To discuss biosensors and signaling networks within DNA-based artificial cells.

Main Methods:

Review of predominant studies in DNA nanotechnology for artificial cell construction.
Analysis of DNA nanostructures for protein mimicking and cellular integration.
Examination of DNA-based signaling networks and biosensors.

Main Results:

DNA nanotechnology enables diverse morphologies for biomimicking applications.
Artificial cells can be engineered for signal recognition, transduction, and output.
DNA-based systems show potential for monitoring cellular microenvironments and feedback networks.

Conclusions:

DNA nanotechnology is a powerful tool for developing functional artificial cells.
Further research is needed to address challenges and guide future designs.
DNA-based artificial cells hold promise for synthetic biology and biomedical applications.