Human 8-cell-like cells discovered
Bradley P Balaton1, Vincent Pasque1
1KU Leuven-University of Leuven, Department of Development and Regeneration, Leuven Institute for Single-Cell Omics (LISCO), Leuven Stem Cell Institute, Leuven, Belgium.
Abstract:
Human naive pluripotent stem cells have the remarkable ability to generate blastoids comprising trophectoderm, epiblast, and hypoblast-like cells. In this issue, Taubenschmid-Stowers et al. (2022) show that human naive pluripotent stem cell cultures contain cells that resemble the 8-cell human embryo, providing a model to study zygotic genome activation.
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