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Updated: Sep 26, 2025

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate HoLEP.
Published on: March 6, 2018
Medical Treatment of Benign Prostatic Hyperplasia
Alexander Plochocki1, Benjamin King1
1Department of Urology, University of Vermont Medical Center, 111 Colchester Avenue, Burlington, VT 05401, USA.
Abstract:
In this article, we review the primary medical treatments of BPH-associated male LUTS, with a focus on physiology, indications, and side effects. We cover selective alpha-1 antagonists, anticholinergics, PDE5 inhibitors, 5-alpha reductase inhibitors, and beta-3 agonists. Through a review of the literature, we provide our clinical pathway for the medical management of BPH, generally starting with tamsulosin in most men and progressing to combination therapy based on patient's response and symptoms.
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