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Periapical Healing following Root Canal Treatment Using Different Endodontic Sealers: A Systematic Review
Akshay Khandelwal1, Krishnamachari Janani2, KavalipurapuVenkata Teja3
1Conservative Dentistry and Endodontics, Gajanan Clinic, Kolkata, 700025 West Bengal, India.
Biomed Research International
|July 18, 2022
Summary
Root canal sealants promote periapical tissue healing. This review found significant healing regardless of sealant type, with bioceramic and bioactive options showing superior outcomes in endodontic treatment.
Area of Science:
- Endodontics
- Regenerative Medicine
- Dental Materials Science
Background:
- Periapical tissue healing is essential for successful root canal therapy.
- Endodontic sealants play a critical role in achieving favorable periapical healing outcomes.
- Evaluating the efficacy of different sealants on periapical healing is crucial for clinical practice.
Purpose of the Study:
- To systematically review and analyze the existing literature on the effectiveness of various endodontic root canal sealants in promoting periapical tissue healing.
- To compare the radiographic outcomes and resolution of periapical lesions associated with different types of endodontic sealers.
Main Methods:
- Systematic review conducted following PRISMA 2020 guidelines and registered with PROSPERO (CRD42021239192).
- Searched PubMed Central and Medline databases up to February 2022 for relevant studies.
- Included in vivo clinical trials with a minimum 6-month follow-up evaluating radiographic outcomes and periapical lesion resolution.
Main Results:
- Nine clinical trials met the inclusion criteria; four studies exhibited a high risk of bias.
- Periapical lesions demonstrated significant healing post-endodontic treatment irrespective of the sealant utilized.
- Bioceramic and bioactive sealers indicated more favorable results in periapical healing compared to other types.
Conclusions:
- Endodontic sealants generally support periapical tissue healing following root canal treatment.
- Bioceramic and bioactive sealers may offer enhanced outcomes for periapical lesion resolution.
- Further high-quality research is needed to definitively establish the superiority of specific sealant types, considering the identified risk of bias.
