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Infectious Crystalline Keratopathy Secondary to Mycobacterium chelonae
Clémence Bonnet1,2, Alex C Onishi1, Anthony J Aldave1
1Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, CA; and.
Cornea
|August 29, 2022
Summary
Infectious crystalline keratitis (ICK) can be caused by atypical bacteria like Mycobacterium chelonae. Multimodal imaging and corneal cultures are crucial for diagnosing this rare condition.
Area of Science:
- Ophthalmology
- Microbiology
Background:
- Infectious crystalline keratitis (ICK) is a rare corneal infection.
- It is typically associated with bacterial pathogens, most commonly Streptococcus species.
Observation:
- This case report details a patient with ICK secondary to Mycobacterium chelonae.
- Clinical examination revealed a central corneal stromal thinning with a white stellate opacity.
Findings:
- Anterior segment optical coherence tomography showed a hyperreflective, diamond-shaped opacity.
- In vivo scanning laser confocal microscopy revealed multiple stellate projections.
- Acid-fast cultures confirmed Mycobacterium chelonae as the causative agent.
Implications:
- This case highlights Mycobacterium species as an atypical cause of ICK.
- Multimodal imaging and prompt corneal cultures are essential for accurate diagnosis and treatment.
- Early identification of the pathogen is critical for managing ICK effectively.
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