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Reaction of the Hippocampal Microglia to Hyperbaric Oxygen
O V Kirik1, O S Alekseeva2,3, D L Tsyba2
1Institute of Experimental Medicine, St. Petersburg, Russia. olga_kirik@mail.ru.
Bulletin of Experimental Biology and Medicine
|October 9, 2022
Abstract:
We studied the reaction of rat hippocampal microgliocytes to hyperbaric oxygen at a pressure of 5 ata (absolute atmosphere). Immunohistochemical analysis with selective macrophage marker CD68 (ED1) and microglial marker Iba-1 allowed separate analysis of these two cell populations. It was shown that macrophages do not significantly contribute to reactive changes in the total pool of Iba-1+ hippocampal cells induced by hyperbaric oxygen.
