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Updated: Aug 25, 2025

Chromogenic In Situ Hybridization as a Tool for HPV-Related Head and Neck Cancer Diagnosis
Published on: June 14, 2019
[Human Papillomavirus: screening of cervical and anal cancers]
Basile Pache1, Martine Jacot-Guillarmod1, Martin Hübner2
1Service de gynécologie-obstétrique, Département femme-mère-enfant, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Abstract:
Cervical cancer is preventable through primary and secondary prevention. Vaccination against the human papillomavirus (HPV), the virus necessary for the development of precancerous lesions, can prevent most of them. Screening by cytology for these precancerous (or cancerous) lesions can be replaced by screening for certain types of HPV, high risk (HR-HPV), causing cervical cancer. The presence of HR-HPV on the cervix should raise suspicion of concomitant infection in the anus, as both epithelia are highly susceptible. This attitude is dictated by the increase incidence in anal cancer in the population, which is also HPV-dependent and therefore also potentially preventable through vaccination and screening.
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