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Craniovertebral Junction Instability in the Setting of Chiari Malformation
Yosef M Dastagirzada1, David B Kurland1, Todd C Hankinson2
1Department of Neurological Surgery, Hassenfeld Children's Hospital, NYU Langone Health, NY 462 1st Avenue, Suite 7S4, New York, NY 10016, USA.
Abstract:
Described in the seminal paper by Hans Chiari in 1891, the Chiari I malformation (CMI) is a radiographic diagnosis commonly encountered by neurosurgeons and is often treated surgically with generally positive clinic outcomes. Studies have documented that 1% to 4% of patients undergoing MRI of the brain or cervical spine will be diagnosed with CMI, characterized by greater than 5 mm tonsillar herniation below the foramen magnum. More recently CMI has been described as a spectrum of disease, which includes Chiari 0, Chiari 1.5, and the complex Chiari. Primarily through multicenter clinical outcomes research, our understanding of the pathology continues to evolve.
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