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Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection
Published on: February 9, 2024
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An entropy-driven DNA nanomachine for microRNA detection using a personal glucose meter
Qing Wang1, Yuqiu He1, Shizhen He1
1College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei, 430072, P. R. China. fuanwang@whu.edu.cn.
Chemical Communications (Cambridge, England)
|January 17, 2023
Abstract:
Herein, we developed a reliable and portable biosensor (TDR-PGM nanomachine) for the sensitive detection of microRNA by integrating an efficient toehold-mediated strand displacement reaction module (TDR) and a personal glucose meter (PGM). The system provides a versatile methodology for microRNA detection in real samples and holds broad prospects in point-of-care diagnosis.
