Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

344
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
344
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

103
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
103
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

64
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
64

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Selection and characterization of salt-tolerant plant growth promoting bacteria associated with the endosphere and rhizosphere of perennial glasswort from the Apulia Region (Italy).

Frontiers in plant science·2026
Same author

PRISMA-based review of <i>Pseudomonas</i> spp. in microbial heavy-metal bioremediation: mechanisms and taxonomy.

Frontiers in microbiology·2026
Same author

In Vitro Assessment of Gut Microbiota Modulation Through Functional Biscuits Enriched with Almond By-Products.

Foods (Basel, Switzerland)·2026
Same author

Microbiota in the Early Lives of Sheep: A Short Overview on the Rumen Microbiota.

Animals : an open access journal from MDPI·2026
Same author

Phenotypic and functional characterization of soil <i>Pseudomonas</i> strains reveals multi-metal tolerance and bioremediation potential.

Frontiers in microbiology·2026
Same author

A statistical approach to model soil microbiota versus heavy metals: a case study on soil samples from Foggia, Southern Italy.

Scientific reports·2025

Related Experiment Video

Updated: Aug 8, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

28.7K

Gut-Microbiota, and Multiple Sclerosis: Background, Evidence, and Perspectives.

Clelia Altieri1, Barbara Speranza1, Maria Rosaria Corbo1

  • 1Department of Agriculture, Food, Natural Resources and Engineering (DAFNE), University of Foggia, 71122 Foggia, Italy.

Nutrients
|February 25, 2023
PubMed
Summary

Changes in gut microbiota are linked to multiple sclerosis (MS) and chronic inflammation. Modulating gut bacteria with probiotics may offer a therapeutic approach for MS patients experiencing gastrointestinal issues.

Keywords:
dietdysbiosisgut microbiotamultiple sclerosisprobiotics

More Related Videos

Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research
05:55

Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research

Published on: December 1, 2023

914
Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice
05:44

Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice

Published on: October 13, 2023

1.5K

Related Experiment Videos

Last Updated: Aug 8, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

28.7K
Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research
05:55

Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research

Published on: December 1, 2023

914
Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice
05:44

Author Spotlight: Creating a Versatile Experimental Autoimmune Encephalomyelitis Model Relevant for Both Male and Female Mice

Published on: October 13, 2023

1.5K

Area of Science:

  • Neuroimmunology
  • Microbiome Research
  • Gastroenterology

Background:

  • The human gut microbiota plays a crucial role in maintaining health and is increasingly linked to chronic-degenerative diseases.
  • Alterations in gut microbial composition and function are associated with chronic inflammatory mechanisms.
  • Multiple sclerosis (MS) is a CNS inflammatory demyelinating disease driven by autoimmune responses against myelin.

Purpose of the Study:

  • To delineate key changes in the gut microbiota of MS patients.
  • To explore the implications of these microbial shifts for health and disease.
  • To identify factors influencing gut microbiota in MS and assess its role in immune system modulation.

Main Methods:

  • Review of scientific literature on gut microbiota and MS.
  • Analysis of microbial taxa modifications associated with MS.
  • Assessment of gastrointestinal pain in MS patients via questionnaire.
  • Evaluation of patient willingness to use probiotics for gut microbiota modulation.

Main Results:

  • Gut microbiota alterations are observed in MS patients, potentially influencing immune responses in the gut and brain.
  • Specific microbial taxa are modified in the disease state.
  • Gastrointestinal symptoms are indirectly related to dysbiosis in MS.
  • MS patients show interest in probiotic interventions.

Conclusions:

  • Gut microbiota dysbiosis is implicated in the pathogenesis and progression of MS.
  • Microbiota modulation, particularly through probiotics, presents a potential therapeutic avenue for MS.
  • Further research is warranted to fully understand the gut-brain axis in MS and optimize microbial-based therapies.