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Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury
Published on: November 9, 2018
Perfusion Imaging of Traumatic Brain Injury
Nathan W Churchill1, Simon J Graham2, Tom A Schweizer3
1Neuroscience Research Program, Saint Michael's Hospital, 209 Victoria Street, Toronto, ON M5B 1M8, Canada; Keenan Research Centre for Biomedical Science of St. Michael's Hospital, 209 Victoria Street, Toronto, ON M5B 1M8, Canada; Physics Department, Toronto Metropolitan University, 60 St George St, Toronto, ON M5S 1A7, Canada.
Abstract:
The mechanisms for regulating cerebral blood flow (CBF) are highly sensitive to traumatic brain injury (TBI). The perfusion imaging technique may be used to assess CBF and identify perfusion abnormalities following a TBI. Studies have identified CBF disturbances across the injury severity spectrum and correlations with both acute and long-term indices of clinical outcome. Although not yet widely used in the clinical context, this is an important area of ongoing research.
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