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Updated: Jul 29, 2025

High-throughput Detection Method for Influenza Virus
Published on: February 4, 2012
The convergence epidemic volatility index (cEVI) as an alternative early warning tool for identifying waves in an
Konstantinos Pateras1,2, Eleftherios Meletis1, Matthew Denwood3
1Department of Public and One Health, School of Medicine, University of Thessaly, Karditsa, Terma Mavromichali St., 43131, Greece.
Abstract:
This manuscript introduces the convergence Epidemic Volatility Index (cEVI), a modification of the recently introduced Epidemic Volatility Index (EVI), as an early warning tool for emerging epidemic waves. cEVI has a similar architectural structure as EVI, but with an optimization process inspired by a Geweke diagnostic-type test. Our approach triggers an early warning based on a comparison of the most recently available window of data samples and a window based on the previous time frame. Application of cEVI to data from the COVID-19 pandemic data revealed steady performance in predicting early, intermediate epidemic waves and retaining a warning during an epidemic wave. Furthermore, we present two basic combinations of EVI and cEVI: (1) their disjunction cEVI + that respectively identifies waves earlier than the original index, (2) their conjunction cEVI- that results in higher accuracy. Combination of multiple warning systems could potentially create a surveillance umbrella that would result in early implementation of optimal outbreak interventions.
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