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Tubular nanomaterials for bone tissue engineering.

Naomi Akiyama¹, Kapil D Patel², Eun Jo Jang³

¹Department of Chemical Engineering, The Cooper Union of the Advancement of Science and Art, New York City, NY 10003, USA.

Journal of Materials Chemistry. B

|June 13, 2023

Summary

Tubular nanomaterials (TN) show promise for tissue engineering, especially bone regeneration. Their unique properties make them ideal for orthopedic coatings and composite scaffolds, enhancing in vivo bone growth.

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Area of Science:

Biomaterials Science
Tissue Engineering
Nanotechnology

Background:

Nanomaterial properties like composition, morphology, and mechanical performance are crucial for tissue engineering applications.
Tubular nanomaterials (TN), including carbon nanotubes (CNTs), titanium oxide nanotubes (TNTs), halloysite nanotubes (HNTs), silica nanotubes (SiNTs), and hydroxyapatite nanotubes (HANTs), offer high surface area, versatile chemistry, and excellent biocompatibility.
TN have demonstrated potential in drug delivery, imaging, and as scaffolds for bone tissue engineering.

Purpose of the Study:

To review recent advancements in tubular nanomaterial-based biomaterials for structural tissue engineering.
To focus specifically on the application of TN in bone tissue regeneration.
To provide a literature review of TN-based orthopedic coatings and composite scaffolds for enhanced in vivo bone regeneration.

Main Methods:

Literature review of recent developments in tubular nanomaterials for tissue engineering.
Analysis of TN applications in orthopedic coatings for metallic implants.
Examination of TN-based composite scaffolds for bone regeneration.

Main Results:

Tubular nanomaterials exhibit significant potential for bone tissue engineering due to their favorable characteristics.
TN-based orthopedic coatings and composite scaffolds can enhance in vivo bone regeneration.
The review highlights the versatility and efficacy of various TNs in biomedical applications.

Conclusions:

Tubular nanomaterials are a promising class of biomaterials for structural tissue engineering, particularly for bone regeneration.
Further research into TN-based materials for orthopedic applications is warranted.
TN offer a viable strategy for developing advanced scaffolds and coatings to improve bone healing.