Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pulmonary Tuberculosis III

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:

Metastasis

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

The Tumor Microenvironment

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Stroke-like Syndromes.

Neuroimaging clinics of North America·2026

Same author

Microstructural changes in juxtacortical white matter regions and their relationship with PASAT score in multiple sclerosis: A proof of concept using machine learning.

Multiple sclerosis and related disorders·2026

Same author

Clinical Manifestations.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025

Same author

Machine and deep learning structural vessel analysis of ruptured and unruptured brain arteriovenous malformations.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2025

Same author

Initial multicenter experience with the Raptor aspiration catheter for treating large vessel occlusion ischemic stroke.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2025

Same author

Imaging Insights into Perineural Tumor Spread.

Radiologic clinics of North America·2025

Same journal

Understanding Acute Encephalopathy.

Neuroimaging clinics of North America·2026

Same journal

Imaging of Acute Encephalopathies.

Neuroimaging clinics of North America·2026

Same journal

Pediatric Encephalopathy: Inflammatory and Autoimmune Etiologies.

Neuroimaging clinics of North America·2026

Same journal

Pediatric Encephalopathy: Inherited Metabolic Disorders.

Neuroimaging clinics of North America·2026

Same journal

Post-Treatment Causes of Encephalopathy.

Neuroimaging clinics of North America·2026

Same journal

Acute Toxic Leukoencephalopathy: Opioid and other Illicit or Abused Drugs and Environmental Toxins.

Neuroimaging clinics of North America·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 25, 2025

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

Intradural Extramedullary Tumors and Associated Syndromes.

Paulo Puac-Polanco¹, Angela Guarnizo², Juan Pablo Cruz³

¹Department of Radiology, Radiation Oncology and Medical Physics, University of Ottawa, Box 232, General Campus Room 1466e, 501 Smyth Road, Ottawa, Ontario K1H 8L6, Canada.

Neuroimaging Clinics of North America

|June 25, 2023

Summary

This summary is machine-generated.

Intradural extramedullary spinal tumors, including schwannomas and meningiomas, often cause neurological deficits. Magnetic resonance imaging (MRI) is crucial for diagnosis and treatment planning.

Keywords:

Cancer Intradural extramedullary MRI Spinal tumors Spine

More Related Videos

Author Spotlight: A Single-Entry Point Endoscopic Intraventricular Approach for Third Ventriculostomy and Pineal Biopsy

Author Spotlight: A Single-Entry Point Endoscopic Intraventricular Approach for Third Ventriculostomy and Pineal Biopsy

Published on: June 28, 2024

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Related Experiment Videos

Last Updated: Jul 25, 2025

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

Author Spotlight: A Single-Entry Point Endoscopic Intraventricular Approach for Third Ventriculostomy and Pineal Biopsy

Author Spotlight: A Single-Entry Point Endoscopic Intraventricular Approach for Third Ventriculostomy and Pineal Biopsy

Published on: June 28, 2024

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Area of Science:

Neurology
Neurosurgery
Radiology

Background:

Intradural extramedullary spinal tumors are neoplasms located within the spinal canal but outside the spinal cord itself.
Common types include schwannomas and meningiomas, with other rare neoplasms also occurring.
Symptoms typically involve gait ataxia, radicular pain, and motor/sensory deficits from spinal cord compression.

Purpose of the Study:

To review the common and less common intradural extramedullary spinal tumors.
To outline the typical clinical presentations of these tumors.
To emphasize the role of MRI in diagnosis and treatment decisions.

Main Methods:

Review of common and rare intradural extramedullary spinal tumors.
Description of clinical presentations associated with spinal cord compression.
Highlighting the diagnostic utility of Magnetic Resonance Imaging (MRI).

Main Results:

Schwannomas and meningiomas are the most frequent intradural extramedullary tumors.
Patients commonly present with symptoms of chronic compressive myelopathy or radiculopathy.
MRI is the preferred imaging modality for detection and evaluation.

Conclusions:

Accurate diagnosis of intradural extramedullary spinal tumors is essential for effective management.
MRI plays a pivotal role in differentiating tumor types and guiding therapeutic strategies.
Understanding the spectrum of these tumors aids in clinical diagnosis and treatment planning.