Naproxen photosensitization demonstrated by challenge

Area of Science:

• Dermatology
• Pharmacology

Background:

• Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for pain and inflammation.
• Photosensitivity reactions are known side effects of some medications.

Observation:

• A patient vacationing in Hawaii developed a significant photosensitivity reaction.
• The reaction was confirmed to be induced by naproxen through a challenge test.

Findings:

• Naproxen can cause marked photosensitivity, posing a risk to travelers.
• This reaction is likely underreported in clinical practice.

Implications:

• Healthcare providers should counsel patients on potential photosensitivity risks associated with naproxen, particularly during travel.
• Further investigation into the incidence of naproxen-induced photosensitivity is warranted.